Lithium citrate

Lithium citrate

Names
Other names Trilithium citrate trilithium 2-hydroxypropane-1,2,3-tricarboxylate
Identifiers
CAS Number	919-16-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:64735
ChEMBL	ChEMBL1201170 Y
ChemSpider	12932 Y
DrugBank	DB14507
ECHA InfoCard	100.011.860
EC Number	213-045-8
PubChem CID	13520
RTECS number	TZ8616000
UNII	3655633623 Y
CompTox Dashboard (EPA)	DTXSID70883185
InChI InChI=1S/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 Y Key: WJSIUCDMWSDDCE-UHFFFAOYSA-K Y InChI=1/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 Key: WJSIUCDMWSDDCE-DFZHHIFOAV
SMILES [Li+].[Li+].[Li+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-]
Properties
Chemical formula	Li3C6H5O7
Molar mass	209.923 g mol−1
Appearance	Odorless white powder
Melting point	decomposes at 105 °C (221 °F; 378 K)
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H319
Precautionary statements	P305+P351+P338
Flash point	N/A
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Lithium citrate (Li₃C₆H₅O₇) is a lithium salt of citric acid that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder. There is extensive pharmacology of lithium, the active component of this salt.

Lithia water contains various lithium salts, including the citrate.

History

An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948 after the Food and Drug Administration banned its use in soda.

Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder. It can be administered orally in the form of a syrup.